The Monroe County health department reported the second local death from COVID-19 on Monday morning.
The patient died at Unity Hospital, the health department said.
"I would like to express my sincerest sympathy for the individual’s family and friends," said public health commissioner Dr. Michael Mendoza.
"Due to privacy issues, I am unable to release details about this individual," Mendoza said.
The county's first COVID-19 death was last week.
The health department also confirmed 12 new cases of COVID-19 overnight and one more Monday afternoon. Of those new cases, three are in people who are older than 80, the department said.
By Monday afternoon, both the University of Rochester and the Rochester Institute of Technology had reported cases in their students or staff.
A total of 11 people in Monroe County were hospitalized for coronavirus treatment as of Monday morning, the county said. Five of those were in intensive care units.
Mendoza said the number of people being treated in ICUs can help foretell the impact of COVID-19 locally.
"We're paying very close attention to how the number of hospitalizations and the number of I-C-U admissions is faring relative to our capacity as a community," Mendoza said.
According to the state health department, there are 132 ICU beds in Monroe County.
Nearly 400 people in the county were under mandatory quarantine or isolation, "but EVERYONE should be staying at home except for essential activities," the health department said.
While testing supplies are limited, people whose symptoms have landed them in the hospital are among the groups the county is prioritizing for diagnosis.
"A hospitalized patient who tests negative can be removed from isolation, which saves PPE usage," the county said, referring to the personal protective gear for medical workers that has also been in short supply.